Is this the one that's a flu/Covid combo? I live in Europe and have been looking forward to it - especially since the flu part covers way more variants than traditionally - no longer a need to depend on flawed predictions as to what variants will be predominant. Also no longer a need for two sore arms.
So in at least two fields in which the US still leads (biomedical research, AI), government action is actively harming their ability to compete because of ideological or political reasons.
The subversion of scientific expertise to replace it with podcasters and political sycophants is one of the biggest disasters of the current years.
The very concept of merit has been destroyed and replaced with judgement calls on celebrity (necessary for leadership role) and subservience to the political whims of the last 15 minutes (and you had better switch in the next 15 minutes or you're out).
> Prasad was also behind the rejection of a closely watched gene therapy for Huntington’s disease made by UniQure
This guy is a disaster. But really it's not just him. It's the entire organizational structure that puts him, or any other one person, in the position that they have the power to do this. There is simply no one qualified.
We need to have expert scientists to set up trials and review the design of the trials and conduct the analysis of the data. This is something that is generally objective and not able to be done without skills and experience. But then you have to make a decision based on those results. And the decision is some sort of risk reward trade off. While science can quantify what that tradeoff is, which path to take is fundamentally outside of the scope of science.
Trade offs are not objective determinations at all because they are based on subjective preferences. And therefore it makes no sense to force it into a one size fits all approval or denial by some centralized body. The only rational approach to such a trade off is to allow each individual to choose for themselves. The only person's opinion on whether the risk justifies the reward for the experimental Huntington's disease treatment is the patient's. The best we can do with science is to use it for its intended purpose to produce good data for him to make his choice.
I thought mRNA vaccine was approved by FDA as an emergency measure for Covid. Doesn't it usually take around 10 years of assessment long term effects to approve a vaccine for general use? Especially for a new family of vaccines like mRNA?
So we need CDC approval for the vaccine to be provided to everyone at no cost. But it sounds like if only the FDA approves, the vaccine will be available to anyone willing to pay. Is that correct?
Is this good because flu vaccines are an educated guess as to what will be circulating because it takes so long to culture them all and this will shorten the manufacturing time so the educated guess can take place later in the process (and be more accurate)?
“it’s been 5 years since i’ve taken up smoking and i didn’t die yet, therefore cigarettes are perfectly safe and anyone who disagrees with me doesn’t understand science” - average educated internet science expert
Something I have never understood about the "big pharma makes fake/unnecessary/harmful vaccines" narrative is how folks who believe in it (including those in this comment section) understand these companies' incentives.
In the United States, pharma companies make money when insurance companies (and the government, but less so than in many other nations) buy their product to give to patients. In practice, very few people are paying for vaccines out of pocket.
Insurance companies in particular hate, hate, hate giving anybody money for any reason. They will not pay for something unless you beat them over the head with how well it works. And if they don't believe you, they'll do their own analyses. Better to blow a few million on a study than spend a few billion on unnecessary treatments. (This is the same reason that there's a car-insurance funded highway safety institute crash-testing cars.)
And yet, every year, they insist on making the flu and COVID vaccines free and pushing it on as many people as possible! I guarantee you if you call your insurance company and ask if they think you should get a flu or COVID vaccine, or any vaccine, really, they'll say, yes please.
Why would they do that if these vaccines were going to cost them money by a) being useless or b) being harmful? There is simply no incentive!
The reason everybody wants you to get the damn shot is that the shots work, and the downside risks of them are smaller and cheaper than the downside risks of the things they prevent. Capitalism would make it very difficult to repeatedly sell vaccines that don't work, or hurt you; you might get away with it once, but after that, the reward's just not there.
I don't know how one responds to that, if one distrusts vaccines, other than to suggest a much larger and more complex evil conspiracy than is plausible to most people.
Flu vaccines aren't immunizing vaccines. They protect against specific strains, and half the time they immunize against a strain that doesn't become widespread and do very little or nothing to protect you. They have side effects which vary widely in severity depending on the specific vaccine.
This article has no data about why mRNA flu vaccines will improve these outcomes, and has no data about the risk/benefit ratio or how it was calculated. It doesn't even cite the "studies" it mentions. It's a remarkably bad article written for low information readers by a low information author.
If Prasad thought this needed more research then it needed more research. He and the people he works with have written dozens, maybe hundreds now, of reports that expose studies that lack the rigor for definitive results, have misleading endpoints, have imbalanced arms etc. I get that anything that would slow vaccines down has somehow become political and lots of people would gladly accept the pharmaceutical companies word on things. This is a blindness due to political leanings and not evidence based. If Prasad says it needs more and better data I'd put money on it needing it.
FDA advisors unanimously vote to approve Moderna's mRNA after agency drama
(arstechnica.com)235 points by worik 21 June 2026 | 139 comments
Comments
I’m so curious how someone goes from being a professor to a science denier? I simply can’t imagine that journey.
The very concept of merit has been destroyed and replaced with judgement calls on celebrity (necessary for leadership role) and subservience to the political whims of the last 15 minutes (and you had better switch in the next 15 minutes or you're out).
This guy is a disaster. But really it's not just him. It's the entire organizational structure that puts him, or any other one person, in the position that they have the power to do this. There is simply no one qualified.
We need to have expert scientists to set up trials and review the design of the trials and conduct the analysis of the data. This is something that is generally objective and not able to be done without skills and experience. But then you have to make a decision based on those results. And the decision is some sort of risk reward trade off. While science can quantify what that tradeoff is, which path to take is fundamentally outside of the scope of science.
Trade offs are not objective determinations at all because they are based on subjective preferences. And therefore it makes no sense to force it into a one size fits all approval or denial by some centralized body. The only rational approach to such a trade off is to allow each individual to choose for themselves. The only person's opinion on whether the risk justifies the reward for the experimental Huntington's disease treatment is the patient's. The best we can do with science is to use it for its intended purpose to produce good data for him to make his choice.
In the United States, pharma companies make money when insurance companies (and the government, but less so than in many other nations) buy their product to give to patients. In practice, very few people are paying for vaccines out of pocket.
Insurance companies in particular hate, hate, hate giving anybody money for any reason. They will not pay for something unless you beat them over the head with how well it works. And if they don't believe you, they'll do their own analyses. Better to blow a few million on a study than spend a few billion on unnecessary treatments. (This is the same reason that there's a car-insurance funded highway safety institute crash-testing cars.)
And yet, every year, they insist on making the flu and COVID vaccines free and pushing it on as many people as possible! I guarantee you if you call your insurance company and ask if they think you should get a flu or COVID vaccine, or any vaccine, really, they'll say, yes please.
Why would they do that if these vaccines were going to cost them money by a) being useless or b) being harmful? There is simply no incentive!
The reason everybody wants you to get the damn shot is that the shots work, and the downside risks of them are smaller and cheaper than the downside risks of the things they prevent. Capitalism would make it very difficult to repeatedly sell vaccines that don't work, or hurt you; you might get away with it once, but after that, the reward's just not there.
I don't know how one responds to that, if one distrusts vaccines, other than to suggest a much larger and more complex evil conspiracy than is plausible to most people.
This article has no data about why mRNA flu vaccines will improve these outcomes, and has no data about the risk/benefit ratio or how it was calculated. It doesn't even cite the "studies" it mentions. It's a remarkably bad article written for low information readers by a low information author.
Hard pass until I see some hard data.
Here's the top-line comparison:
Healthcare encounter:
new: 80 (0.4)
existing: 120 (0.6)
Each group had roughly 20k participants, mostly white.
No actual control group, no independent third party study. Junk.